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Common Health Issues in Doberman Pinschers
Von Willebrand Disease (vWd)
vWd is an inherited bleeding disorder where symptomatic dogs present with a
prolonged bleeding time and a factor IX deficiency.
The disease is an
"autosomal recessive", which means that affected animals have two doses
of the mutated gene, and a mild to moderate risk of bleeding. There are 3 categories of vWd Clear, Carrier, and Affected. It should be noted that while Affected dogs are genetically affected the are not typically clinically affected (meaning they rarely have actual bleeding issues). Based on preliminary data, it is believed that about 36% of all Dobermans being
homozygous affected (two of the abnormal gene and at risk for
bleeding), 48% being carriers (one abnormal and one normal gene, no risk
of bleeding), and 16% being homozygous clear (two of the normal
gene). This is a very common disease and probably the most well known "Doberman" disease.
Carriers of the mutant vWD gene are at no risk of bleeding from
vWD, but can transmit the mutant gene to their offspring 50%
of the time. It is important to realize that this DNA test is very
different from the old protein-based factor assay (elisa blood test). The DNA test is
definitive and final, a lifelong, permanent determination of the vWD
status of each dog tested as contrasted to the factor assay, in which
the levels could change drastically over time.
The two companies which offer a DNA test for vWd are:
Please note there are many other diseases that can cause prolonged bleeding including liver issues and anemia.
Hip Dysplasia
Hip dysplasia is the abnormal formation of the hip socket that, in its more severe form, can eventually cause crippling lameness and painful arthritis
of the joints. It is a polygenic trait that is also affected by
environmental factors.
The causes of hip dysplasia arehave been historically considered inheritable, but new research conclusively suggests that environment also plays a large role. To what degree it is genetic and what portion is environmental is a topic of current debate. Environmental influences would include overweight condition, injury at a young age, overexertion on hip joint at a young age, ligament tear at a young age, repetitive motion on forming joint (i.e. jogging with puppy under the age of 1 year). As current studies progress, greater information will help provide procedures to effectively reduce the occurrence of this condition.
Doberman Pinschers have a relatively low incidence of Hip Dysplasia at 6.1 % of those tested.
Elbow Dysplasia
Elbow dysplasia is a condition involving multiple developmental abnormalities of the elbow in a dog, specifically the growth of cartilage or the structures surrounding it. These abnormalities, known as 'primary lesions' give rise to osteoarthritic processes.
Most primary lesions are related to osteochondrosis, which is a disease of the joint cartilage . Other common causes of elbow dysplasia included ununited anconeal process (UAP) and fragmented or ununited medial coronoid process (FCP or FMCP).
The "primary lesion", causes an abnormal level of wear and tear and gradual degradation of the joint, at times disabling or with chronic pain. Secondary processes such as inflammation and osteoarthritis can arise from this damage which increase the problem and add further problems of their own.
Doberman Pinschers have a low incidence of Elbow Dysplasia at 0.8% of those tested.
Cancer
Cancer is an unfortunately common disease of dogs - 1 in 4 dogs will die of cancer according to the Morris Animal Foundation. For dogs over 10 years of age, approximately 50% of deaths are cancer-related. Like humans, there are many types of cancers and many clinical signs seen.
Cancer is an abnormal growth of cells and may be benign (slow-growing, removable) or malignant (aggressive, spreading throughout body). The causes of these cancers are largely unknown, making prevention difficult. Being aware of possible signs of cancer in pets will help provide early detection and care. Cancer can affect any area of the body and any body system. Cancers of the skin, lymph nodes, gastrointestinal tract, blood and bone are common in dogs.
Wobblers
Cardiac issues
Drs Meurs' and Estrada's Cardiomyopathy presentationscan be viewed online at UStream. Click here for details
Albinism
This line, all descended from Padula's Queen Shebah, has produced more than 11,300 Dobermans of which more than 1830 are white albino. In 1982 the AKC Doberman standard was amended to only include black, red, fawn, and blue coats. White coats are no longer allowed AKC registration. In an effort to stem the destruction being caused by the albino line, in 1996 descendents, possible carriers of the albino gene, are tracked by placing them on the z-list and recording a WZ designation in front of their AKC registration number.
Besides the obvious problems of not having melatonin pigment to protect the body, the genes responsible for albinism are closely related to other genes. These genes are responsible for other body functions unrelated to pigmentation such as liver, kidney, and blood functions where problems can develop.
Additionally, behavioral problems have been observed in Dobermans suffering from albinism. These Dobermans have had problems with aggression and adjusting to new situations. The physical and mental challenges accompanying the albino Doberman’s white coat are apparent.
Eye issues
Cataracts- A cataract is an opacity in the lens of a dog’s eye, causing him to have blurry vision. If the cataract is small, it won’t likely disturb the dog’s vision too much, but cataracts must be monitored because the thicker and denser they become, the more likely it is they will lead to blindness.
Cataracts can develop from disease, old age and trauma to the eye, but inherited conditions are the most common cause. Cataracts may be present at birth or develop when a dog is very young-between one and three years of age. A high-incidence of cataracts is also often attributed to diabetes.
PRA (PROGRESSIVE RETINAL ATROPHY) - is an inherited condition in Dobermans. Clinically, visual acuity is diminished, first at dusk, later in daylight. The disease progresses over months or years, to complete blindness. A screening test is available and can be performed by a veterinary ophthalmologist.PHTVL / PHPV {Persistent hyperplastic tunica vasculosa lentis (PHTVL) and Persistent hyperplastic primary vitreous (PHPV)}-refer to the persistence of the embryonic vascular system of the lens. PHTVL /PHPV is a congenital eye anomaly which occurs in many animals as well as in people.
Hypothyroidism
Hernias
A normal umbilical is open so that a mother can nurture the puppy while he resides in the womb. Shortly after birth and under normal conditions, the umbilical area closes because it is no longer needed and infection is prevented by its closure. If the umbilical remains open and does not close properly, a hernia will develop as the inside of the abdomen will no longer have the abdominal wall which secures it into place. The true cause of an umbilical hernia, or the inability of the umbilical area to close properly, is not something that medical science has been able to pinpoint. There is evidence to suggest that the dam can cause an umbilical hernia either by ripping the umbilical cord too close to the skin or being overly zealous with cleaning of the stomach.
Cryptorchidism
Cryptorchidism is the medical term that refers to the failure of one or both testicles (testes) to descend into the scrotum. In most cases of cryptorchidism, the testicle is retained in the abdomen or in the inguinal canal (the passage through the abdominal wall into the genital region through which a testicle normally descends). Sometimes the testicle will be located just under the skin (in the subcutaneous tissues) in the groin region, between the inguinal canal and the scrotum. In cases of abdominal cryptorchidism, the testicle cannot be felt from the outside. Abdominal ultrasound or radiographs may be performed to determine the exact location of the retained testicle. Many dogs will only have one retained testicle, and this is called unilateral cryptorchidism. The testes develop near the kidneys within the abdomen and normally descend into the scrotum by two months of age. In certain dogs it may occur later, but rarely after six months of age. Cryptorchidism may be presumed to be present if the testicles can’t be felt in the scrotum after four months of age. Cryptorchidism occurs in all breeds. Approximately seventy-five percent of the cases of cryptorchidism involve only one retained testicle while the remaining twenty-five percent involve failure of both testicles to descend into the scrotum. The right testicle is more than twice as likely to be retained as the left testicle. Cryptorchidism affects approximately 1.2% of all dogs.